WHAT ARE SOME OF THE RISKS ASSOCIATED WITH BONE-TARGETING MEDICINES?
Do not take bone-targeting medicines if you have low blood calcium (hypocalcemia) or are allergic to any of the ingredients in the medicine. Call your doctor or go to the nearest emergency room right away if you have any symptoms of a serious allergic reaction, including:
- Low blood pressure (hypotension)
- Trouble breathing
- Throat tightness
- Swelling of the face, lips, or tongue
- Rash, itching, or hives
Some of the possible side effects of bone-targeting medicines include low calcium levels in your blood (hypocalcemia), which could be life-threatening, severe jaw bone problems (osteonecrosis), unusual thigh bone fractures (atypical femoral fracture), and possible harm to your unborn baby.2
- Unusual thigh bone fractures (atypical femoral fractures) can occur while taking bone-targeting medicines. Symptoms can include new or unusual pain in your hip, groin, or thigh.4,5
- Possible harm to your unborn baby: Bone-targeting medicines may harm your unborn baby. Tell your doctor right away if you are pregnant, plan to become pregnant, or suspect you are pregnant.
If you are already on a bone-targeting medicine and you experience these or any other unusual symptoms, contact your doctor.